Venetia Lanyon, beautiful, intelligent and independent, lives in comfortable seclusion in rural Yorkshire with her precocious brother Aubrey. Her future seems safe and predictable: Either marriage to the respectable but dull Edward Yardley, or a life of peaceful spinsterhood.
In Richmond, Virginia, young lovers are dying. So far, four couples in the area have disappeared, only to be found months later as mutilated corpses. When the daughter of the president's newest drug czar vanishes along with her boyfriend, Dr Kay Scarpetta knows time is short. Following a macabre trail of evidence that ties the present homicides to a grisly crime in the past, Kay must draw upon her own personal resources...